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Israeli researchers use computer design to boost cancer-fighting immune cells
An engineered T-cell receptor showed stronger tumour-killing in mice.
Bar-Ilan University and Weizmann Institute researchers published in Science Advances a computationally designed T-cell receptor, SET. Engineered cells showed stronger cancer-killing in the lab, and in mice with human tumours, treated tumours were about 35% smaller after 83 days.
What holds up
- ✓Published in Science Advances by Cyrille Cohen's team with Weizmann collaborators.
- ✓Results come from lab and mouse experiments.
What doesn't yet
- ?Mouse results may not translate to humans; no clinical trials yet.
- ?The 35% figure has not been independently replicated.
Ask before you share
- →What safety risks come with re-engineered receptors?
- →How does it compare with approved CAR-T and TCR therapies?
- →What is the realistic path to human trials?
Sources & original reporting
- [1]EurekAlert! / Bar-Ilan University · Published 23 Sept 2026 · sciencesources.eurekalert.org